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Publications

Dr. John Crocker has over 136 publications in various areas of Pediatric Nephrology and basic science. He also has a textbook published, and a number of textbook chapters.

Dr. Philip Acott has over 55 publications on various basic science and nephrology/endocrinology areas.

Acott PD, Ali G, Lewis NA. The Cr(II) Reduction of Pentane-2,4-
dionatobis(ethylenediamine)cobalt(III). An Apparent Failure of the Product Criterion for Assigning Inner-sphere Mechanisms. Inorg. Chim. Acta. 99, 169-176. 1985.

Acott PD, Murphy MG, Crocker JFS, Ogborn MR. Quantitative Measurement of Phthalates in Small Samples of Mammalian Tissue. Bull Env Cont Toxicol. 38: 3. 1986.

Acott PD, Crocker JFS, Ogborn MR. : Chronic Renal Failure in the Rat: A Surgical Model for Long Term Toxicological Studies. J Pharmacol Methods. 18: 81-88. 1987.

Crocker JFS, Safe S, Acott PD. Effects of Chronic Phthalate Exposure on the Kidney. J Toxicol and Env Health. 23: 433-444. 1988.

Acott PD, Finley J, Cole DEC. Paradoxical use of Clonidine in Orthostatic Hypertension (Letter to the Editor). J Ped. 116(4): 666-667. 1990.

Couch RM, Acott PD, Wong GWK. Early Onset of Fatal Cerebral Edema in Diabetic Ketoacidosis. Diabetes Care. 14(1): 78-79. 1991.

Crocker JFS, Acott PD, Atkinson CM, McLellan H, Lawen J, Bitter-Suermann H, Lau H. Transplantation in Retinal-Renal Syndrome. Transplant Proc. 26(1): 60-61. 1994.

McLellan RA, Drobitch RK, McLellan H, Acott PD, Crocker JFS, Renton KW. Norfloxacin Interferes with Cyclosporin A Disposition in Pediatric Renal Transplant Patients. J Clin Pharm and Therap. 58: 322-329. 1995.

Crocker JFS, Schenk ME, Hamilton DA, Cole DEC, and Acott PD. Thyroid Hormone Modulation of Glucocorticoid Induced Polycystic Renal Disease. J Amer Soc Neph. 7 (4): 633-634. 1996.

Acott PD, Wade AW, Lee SHS, Bitter-Suermann H, Lawen JG, Crocker JFS. Infection Concomitant with Pediatric Renal Allograft Rejection. Transplantation. 62(5): 689-698. 1996.

Loh K-C, Salisbury SR, Acott PD, Gillis R, Crocker JFS. Central Precocious Puberty and Chronic Renal Failure: A Reversible Condition Post Renal Transplantation. Journal Pediatric Endocrinology and Metabolism. 10(5): 539-545. 1997.

Murphy MG, Crocker JFS, Lee SHS, Acott PD, Her H. Sequestration of Coenzyme A by the Industrial Surfactant, Toximul MP8: A Possible Role in the Inhibition of Fatty-acid ? -Oxidation in a Surfactant/Influenza B Virus Mouse Model for Acute Hepatic Encephalopathy. Biochim Biophys Acta. 1361: 103-113. 1997.

Wade A, McDonald A, Acott PD, Lee S, Crocker J. Human Herpes Virus-6 (HHV6) or Epstein-Barr Virus (EBV) Infection and Acute Allograft Rejection in Pediatric Kidney Transplant Recipients: Greater Risk for Immunologically Naive Recipients. Transplant Proc. 30(5): 2091-93. 1998.

Crocker JFS, Digout SC, Lee SH, Rozee KR, Renton K, Field CA, Acott PD, Murphy MG. Effects of Antipyretics on the Incidence of Mortality Due to Influenza B Virus in a Mouse Model of Reye's Syndrome. Clin Invest Med . 21(4/5): 192-202. 1998.

Acott PD, McLellan H, Wade A, McDonald A, Crocker J. Transplantation Issues in Pediatric Retinal-Renal Syndromes. Transplant Proc. 30(5): 1997-99. 1998.

JFS Crocker, Wade AW, McDonald ATJ, McLellan DH, Lawen J, Bitter-Suermann H, Acott PD. Pediatric Transplant Organ Loss and Implications for Program Development. Canadian Medical Association Journal . 159(3): 229-235. 1998.

Crocker J, Renton K, Wade A, McLellan H, Acott PD. Acute Allograft Rejection Following Conversion to a New Cyclosporin A Formulation in Pediatric Renal Transplant Patients. Transplant Proc. 30(5): 2002-05. 1998.

Acott PD, Lee S. HHV-6 in Kidney Transplantation: Expert working group on HHV-6 and 7 Laboratory Diagnosis and Testing. Canada Communicable Disease Report. 26(S4): 14-15. 2000.

Acott PD, Lawen J, Lee S, Crocker JFS. Basiliximab Versus ATG/ALG Induction in Pediatric Renal Transplants: Comparison of Herpes Virus Profile and Rejection Rates. Transplant Proc. 33(7-8): 3180-3. 2001.

French CG, Lawen JG, Acott PD, Crocker JFS. Extravesical Neouretercystotomy With and Without Internalized Ureteric Stents in Pediatric Renal Transplantation. Pediatr Transplantation . 5(1): 21-26. 2001.

Crocker JFS, Acott PD, Carter J, Lirenman D, MacDonald GW, McAllister M, McDonnell M, Shea S, Bawden HN. Neuropsychological Outcome in Children with Acquired or Congenital Renal Disease. Pediatr Nephrol. 17(11): 908-12. 2002.

Resch L, Acott PD, Fraser RB, Yu W, Lawen JG, Crocker JFS, Wright JR. T-Cell/Periodic Acid-Schiff stain: A Useful Tool in the Evaluation of Tubulointerstitial Infiltrates as a Component of Renal Allograft Rejection. Ann Diagn Pathol. 6(2): 122-4. 2002.

Rozee KR, Acott PD, Lee SHS, Crocker JFS, Gough D, MacDonald J, Evan J, Murphy MG. Elevated Anticardiolipin antibodies in Acute Liver Failure. Biochem. Biophys Acta. 1637(3): 183-6. 2003.

Stewart WA, Acott PD, Salisbury S, Lang BA. Bone Mineral Density in Juvenile Dermatomyositis: Assessments Using Dual Energy X-ray Absorptiometry. Arthritis Rheum. 48(8): 2294-8. 2003.

Acott PD, Crocker JFS, Wong J. Decreased Bone Mineral Density in Pediatric Renal Transplant Population. Pediatr Transplantation . 7: 358-363. 2003.

Acott PD and Pernica J. Growth hormone therapy before and after pediatric renal transplant. Pediatr Transplantation . 7: 426-440. 2003.

Tee JB, Acott PD, McLellan HD, Crocker JFS. Phenotypic heterogeneity in pediatric autosomal dominant polycystic kidney disease at first presentation: a single-centre 20 year review. American Journal of Kidney Disease . 43, No.2, 296-303. 2004.

Wong JA, Renton KW, Crocker JFS, O'Regan PA, Acott PD. The Determination of Pamidronate in Human whole blood and urine by reversed-phase HPLC with Fluorescence Detection. Biomed Chromatogr. 18(2): 98-101. 2004.

Acott PD, Crocker J, Lee S. Simulect and HHV-6 in Pediatric Renal Transplantation. Transplant Proc. 36(2): 483S-486S. 2004.

Bawden HN, Acott PD, Carter J, Lirenman D, MacDonald GW, McAllister M, McDonnell MC, Shea S, Crocker JFS. Neuropsychological functioning in end-stage renal disease. Arch Dis Child. 89(7): 644-7. 2004.

Acott PD, Crocker J, Lee S, Evans J, O'Regan P, Al-Khalidi M, Geldenhuys L, Murphy M. Effects of Insulin-like Growth Factor-Type 1 on Weight Gain and Hepatic Glycogen During Early Development in a Surfactant/Virus Mouse Model of Acute Liver Failure: Correlation with Mortality. Hepatol Res. 29(1): 42-50. 2004.

Lang B, Acott PD, Stewart W. Reply re: Bone Mineral Density in Juvenile Dermatomyositis: Assessments Using Dual Energy X-ray Absorptiometry. Arthritis Rheum. 50(7): 2379-2380. 2004.

Renton KW, Crocker JFS, McLellan H, Acott PD. A comparison of the pharmacokinetics of tacrolimus and microemulsified ciclosporin in pediatric renal transplant recipients. Eur J Clin Pharmacol. 60(6): 421-6. 2004.

Acott PD, Lawen JG, Crocker JFS. Third Dose of Basiliximab in Pediatric Renal Transplantation. Transplant Proc. 36(9): 2628-31. 2004.

Hardy KW, Crocker JFS, McLellan H, Renton KW, Acott PD. Paradoxical cyclosporine A requirements in pediatric renal transplants receiving high dose steroids. J Clin Pharmacol. 45(2): 161-7. 2005.

Acott PD, Wong JA, Lang B, Crocker JFS. Pamidronate Treatment of Pediatric Fracture Patients on Chronic Steroid Therapy. Pediatr Nephrol. 20(3): 368-73. 2005.

Crocker JFS, Acott PD. A GP's Checklist: Gross Hematuria. The Canadian Journal of CME. 88-90. 2005.

Goralski KB, Acott PD, Fraser AD, Worth D, Sinal CJ. Brain Cyclosporine A Levels Are Determined By Ontogenic Regulation Of Mdr1a Expression. Drug Metab Dispos. 34: 288-295. 2006.

Acott PD. Home fingerprick sampling for immunosuppressant drug monitoring in pediatric renal transplant patients. Nat Clin Pract Nephrol. 2(6): 304-305. 2006.

Barber CE, Hewlett TJ, Geldenhuys L, Kiberd BA, Acott PD, Hatchette TF. BK virus nephropathy in a heart transplant recipient: case report and review of the literature. Transpl Infect Dis. 8(2): 113-21. 2006.

Wornell P, Dyack S, Crocker J, Yu W, Acott PD. Fabry Disease and nephrogenic diabetes insipidus. Pediatr Nephrol. 21(8):1185-8. 2006.

Acott PD, Crocker JF, Renton KW. Evaluation of performance factors affecting two formulations of cyclosporine in pediatric renal transplant patients. Transplant Proc. 38(9):2835-41. 2006.

Acott PD. Polyoma Virus in Renal Transplantation. Pediatr Transplant. 10(7): 856-860. 2006.

Acott PD, Wong JA, Crocker JFS, Lang B, O'Regan P, Renton KW. The Distribution and Excretion of Pamidronate in Pediatric Renal and Rheumatological Patients. Eur J Clin Pharmacol. 62(12):1013-1019. 2006.

Acott PD, O'Regan PA, Lee SH, Crocker JF. Utilization of Vero Cells for Primary and Chronic BK Virus Infection. Transplant Proc. 38(10):3502-5. 2006.

Acott PD, Hirsch HH. BK Virus Infection, Replication and Diseases in Pediatric Kidney Transplantation. Pediatr Nephrol. 22(9):1243-50. 2007.

Murphy MG, Crocker JFS, O'Regan P, Lee SH, Geldenhuys L, Dooley K, Al-Khalidi M, Acott PD. Carnitine, Acylcarnitine and Amino Acid Profiles Analyzed by Tandem Mass Spectrometry in a Surfactant/Virus Mouse Model of Acute Hepatic Encephalopathy. Chemosphere. 68(9):1692-8. 2007.

Upham J, Acott PD, O'Regan P, Crocker JFS, Geldenhuys L, Murphy MG. The Pesticide Adjuvant, Toximul, alters Hepatic Metabolism through Effects on Downstream Targets of PPARa. Biochim Biophys Acta. 1772(9):1057-64. 2007.

Wornell P, Crocker J, Wade A, Dixon J, Acott P. An Acadian variant of the Fanconi Syndrome. Pediatr Nephrol. 22(10):1711-5. 2007.

Al-Khalidi M, Acott PD, Crocker JFS, Lee SH, O'Regan PA, Murphy MG. Effects of Two Formulations of the Toximul Class Class of Industrial Surfactants on the Glycogen Content of Human HepG2 Cells. J Toxicol Environ Health A. 70(20):1772-5. 2007.

Acott PD, O'Regan PA, Lee SH, Crocker JFS. In vitro effect of cyclosporin A on primary and chronic BK polyoma virus infection in Vero E6 cells. Transpl Infect Dis. 10(6):385-390. 2008.

Acott PD. Current Treatment of Polyoma BK Nephropathy in Pediatric Renal Transplant Patients. Pediatr Transplant. 12(7):721-723. 2008.

Acott PD, O'Regan PA, Lee SH, Crocker JFS. Suppression of early and chronic BK polyoma virus infection by mycophenolic acid in Vero cells. Transpl Int. 22(2):225-31. 2009.

Harvie S, McLeod L, Acott PD, Walsh E, Abdollel M, Macken M. Abnormal Antenatal Sonogram: An Indicator of Disease Severity in Children with Posterior Uretharal Valves.. Can Assoc Radiol J. 60(4):185-9. 2009.